66.
Bickelman C, Ferries L, Eaton RP. Impotence related to anabolic steroid use
in a body builder. Response to clomiphene citrate. West J Med 1995;162:
158
60
.
67.
Menon DK. Successful treatment of anabolic steroid-induced azoospermia
with human chorionic gonadotropin and human menopausal gonado-
tropin. Fertil Steril 2003;79(Suppl 3):1659
61
.
68.
Tan RS, Vasudevan D. Use of clomiphene citrate to reverse premature
andropause secondary to steroid abuse. Fertil Steril 2003;79:203
5
.
69.
Weinstein RL, Reitz RE. Pituitary-testicular responsiveness in male hypogo-
nadotropic hypogonadism. J Clin Invest 1974;53:408
15
.
70.
Moskovic DJ, Katz DJ, Akhavan A, Park K, Mulhall JP. Clomiphene citrate is
safe and effective for long-term management of hypogonadism. BJU Int
2012;110:1524
8
.
71.
de Luis DA, Aller R, Cu
±
ellar LA, Terroba C, Romero E. [Anabolic steroids and
gynecomastia. Review of the literature]. An Med Interna 2001;18:489
91
.
72.
Braunstein GD. Clinical practice. Gynecomastia. N Engl J Med 2007;357:
1229
37
.
73.
Ferrando J, Grimalt R, Alsina M, Bulla F, Manasievska E. Unilateral gyneco-
mastia induced by treatment with 1 mg of oral
f
nasteride. Arch Dermatol
2002;138:543
4
.
74.
Green L, Wysowski DK, Fourcroy JL. Gynecomastia and breast cancer dur-
ing
f
nasteride therapy. N Engl J Med 1996;335:823
.
75.
Lee SC, Ellis RJ. Male breast cancer during
f
nasteride therapy. J Natl Cancer
Inst 2004;96:338
9
.
76.
Traish AM, Hassani J, Guay AT, Zitzmann M, Hansen ML. Adverse side ef-
fects of 5
a
-reductase inhibitors therapy: persistent diminished libido and
erectile dysfunction and depression in a subset of patients. J Sex Med
2011;8:872
84
.
77.
Jameel JKA, Kneeshaw PJ, Rao VSR, Drew PJ. Gynaecomastia and the plant
product
‘‘
Tribulis terrestris
’’
. Breast 2004;13:428
30
.
78.
Toorians AWFT, Bovee TFH, de Rooy J, Stolker LAAM, Hoogenboom RLAP.
Gynaecomastia linked to the intake of a herbal supplement forti
f
ed with
diethylstilbestrol. Food Addit Contam Part A Chem Anal Control 2010;
27:917
25
.
79.
Deepinder F, Braunstein GD. Drug-induced gynecomastia: an evidence-
based review. Expert Opin Drug Saf 2012;11:779
95
.
80.
Dickson G. Gynecomastia. Am Fam Physician 2012;85:716
22
.
81.
Hanavadi S, Banerjee D, Monypenny IJ, Mansel RE. The role of tamoxifen in
the management of gynaecomastia. Breast 2006;15:276
80
.
82.
Spano F, Ryan WG. Tamoxifen for gynecomastia induced by anabolic ste-
roids? N Engl J Med 1984;311:861
2
.
83.
Babigian A, Silverman RT. Management of gynecomastia due to use of
anabolic steroids in bodybuilders. Plast Reconstr Surg 2001;107:240
2
.
84.
Neild D. Gynaecomastia in bodybuilders. Br J Clin Pract 1995;49:172
.
85.
Boccardo F, Rubagotti A, Battaglia M, di Tonno P, Selvaggi FP, Conti G,
et al. Evaluation of tamoxifen and anastrozole in the prevention of gyneco-
mastia and breast pain induced by bicalutamide monotherapy of prostate
cancer. J Clin Oncol 2005;23:808
15
.
86.
Lawrence SE, Faught KA, Vethamuthu J, Lawson ML. Bene
f
cial effects of
raloxifene and tamoxifen in the treatment of pubertal gynecomastia. J
Pediatr 2004;145:71
6
.
87.
Parker LN, Gray DR, Lai MK, Levin ER. Treatment of gynecomastia with
tamoxifen: a double-blind crossover study. Metabolism 1986;35:705
8
.
88.
Buvat J, Ardaens K, Lemaire A, Gauthier A, Gasnault JP, Buvat-Herbaut M.
Increased sperm count in 25 cases of idiopathic normogonadotropic
oligospermia following treatment with tamoxifen. Fertil Steril 1983;39:
700
3
.
89.
de la Torre Abril L, Ramada Benlloch F, S
±
anchez Ballester F, Ordo
~
no
Domínguez F, Ulises Juan Escudero J, Naval
±
on Verdejo P, et al. [Manage-
ment of male sterility in patients taking anabolic steroids]. Arch Esp Urol
2005;58:241
4
.
90.
Dony JM, Smals AG, Rolland R, Fauser BC, Thomas CM. Effect of lower
versus higher doses of tamoxifen on pituitary-gonadal function and sperm
indices in oligozoospermic men. Andrologia 1985;17:369
78
.
91.
Tsourdi E, Kourtis A, Farmakiotis D, Katsikis I, Salmas M, Panidis D. The ef-
fect of selective estrogen receptor modulator administration on the
hypothalamic-pituitary-testicular axis in men with idiopathic oligozoosper-
mia. Fertil Steril 2009;91:1427
30
.
92.
Veldhuis JD, Dufau ML. Estradiol modulates the pulsatile secretion of bio-
logically active luteinizing hormone in man. J Clin Invest 1987;80:631
8
.
93.
Vermeulen A, Comhaire F. Hormonal effects of an antiestrogen, tamox-
ifen, in normal and oligospermic men. Fertil Steril 1978;29:320
7
.
94.
Finkelstein JS, Lee H, Burnett-Bowie S-AM, Pallais JC, Yu EW, Borges LF,
et al. Gonadal steroids and body composition, strength, and sexual func-
tion in men. N Engl J Med 2013;369:1011
22
.
95.
Dohle GR, Smit M, Weber RFA. Androgens and male fertility. World J Urol
2003;21:341
5
.
96.
Lombardo F, Sgr
²
o P, Salacone P, Gilio B, Gandini L, Dondero F, et al. Andro-
gens and fertility. J Endocrinol Invest 2005;28:51
5
.
97.
Bagatell CJ, Bremner WJ. Androgens in men
uses and abuses. N Engl
J Med 1996;334:707
14
.
98.
Ko EY, Siddiqi K, Brannigan RE, Sabanegh ES Jr. Empirical medical therapy
for idiopathic male infertility: a survey of the American Urological Associa-
tion. J Urol 2012;187:973
8
.
99.
Basaria S. Androgen abuse in athletes: detection and consequences. J Clin
Endocrinol Metab 2010;95:1533
43
.
100.
Gazvani MR, Buckett W, Luckas MJ, Aird IA, Hipkin LJ, Lewis-Jones DI. Con-
servative management of azoospermia following steroid abuse. Hum
Reprod 1997;12:1706
8
.
101.
Knuth UA, Maniera H, Nieschlag E. Anabolic steroids and semen parame-
ters in bodybuilders. Fertil Steril 1989;52:1041
7
.
102.
Turek PJ, Williams RH, Gilbaugh JH 3rd, Lipshultz LI. The reversibility of
anabolic steroid-induced azoospermia. J Urol 1995;153:1628
30
.
103.
Grokett BH, Ahmad N, Warren DW. The effects of an anabolic steroid (ox-
androlone) on reproductive development in the male rat. Acta Endocrinol
(Copenh) 1992;126:173
8
.
104.
Hsieh T-C, Pastuszak AW, Hwang K, Lipshultz LI. Concomitant intramus-
cular human chorionic gonadotropin preserves spermatogenesis in men
undergoing testosterone replacement therapy. J Urol 2013;189:647
50
.
105.
Vicari E, Mongioì A, Calogero AE, Moncada ML, Sidoti G, Polosa P, et al.
Therapy with human chorionic gonadotrophin alone induces spermato-
genesis in men with isolated hypogonadotrophic hypogonadism
long-
term follow-up. Int J Androl 1992;15:320
9
.
106.
Kim S-O, Ryu KH, Hwang IS, Jung SI, Oh KJ, Park K. Penile growth in
response to human chorionic gonadotropin (hCG) treatment in patients
with idiopathic hypogonadotrophic hypogonadism. Chonnam Med J
2011;47:39
42
.
107.
Gardner FH, Nathan DG, Piomelli S, Cummins JF. The erythrocythaemic
effects of androgen. Br J Haematol 1968;14:611
5
.
108.
Gooren LJ. Androgens and male aging: current evidence of safety and
ef
f
cacy. Asian J Androl 2010;12:136
51
.
109.
Stergiopoulos K, Brennan JJ, Mathews R, Setaro JF, Kort S. Anabolic
steroids, acute myocardial infarction and polycythemia: a case report and
review of the literature. Vasc Health Risk Manag 2008;4:1475
80
.
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