be met with poor libido-decreasing satisfaction and quality
of life. Carefully designed placebo-controlled trials to assess
the risks and benefits of both testosterone and oestrogen are
Conflicts of interest:
Larry I. Lipshultz has been a clinical trials
participant, consultant, and speaker for Auxilium and Endo. The other
authors have nothing to disclose.
Finkelstein JS, Lee H, Burnett-Bowie SA, et al. Gonadal steroids and
body composition, strength, and sexual function in men. N Engl J
Med 2013;369:1011–22.
Carani C, Rochira V, Faustini-Fustini M, Balestrieri A, Granata AR.
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natural model of aromatase de±ciency. Clin Endocrinol (Oxf) 1999;
Mohamed O, Freundlich RE, Dakik HK, et al. The quantitative ADAM
questionnaire: a new tool in quantifying the severity of hypogo-
nadism. Int J Impot Res 2010;22:20–4.
Ranjith Ramasamy
Jason M. Scovell
Jason R. Kovac
Larry I. Lipshultz*
Department of Urology, Baylor College of Medicine, Houston, TX, USA
*Corresponding author. 6624 Fannin Street, #1700,
Houston, TX 77030, USA.
E-mail address:
(L.I. Lipshultz).
January 13, 2014
Published online ahead of print on January 23, 2014
EUROPEAN UROLOGY 65 (2014) 1224–1225