Peyronie's Disease
One form of erectile dysfunction is a curvature of the penis called Peyronie’s disease. Peyronie's disease is an acquired inflammatory condition of the penis where a formation of plaque develops under the skin of the penis, leading to curved and/or painful erections.
Symptoms of Peyronie's Disease
You or your doctor may notice an abnormal hardening of the tissue below the skin - in one area along the shaft of the penis. Plaque most commonly occurs on the upper side of the penis, but can also form on the bottom or side of the penis. In some men, plaque occurs around the entire penis.
During erection, there may be:
- A bend in the penis, which usually begins at the area where you feel the scar tissue or hardening
- Narrowing of the penis
- Pain
- Problems with penetration or pain during intercourse
- Shortening of the penis
- Inability to maintain the erection
Treatments for Peyronie's Disease
If the symptoms do not improve over time, treatment may be necessary. Treatments may include:
Oral Medications
Be sure to ask your doctor about the following medications.
- Trental
- Arginine
- Vitamin E
- Daily PDE5i
Penile Injections
Injections of medication directly into the plaque are a popular option for men because it allows for higher doses of medication to be directed to the plaque. It is also an attractive option for those who are reluctant to have surgery. Be sure to ask your doctor about the following types of penile injections:
- Verapamil injections
- Interferon injections
- Collagenase injections (in testing phase)
Surgical Repair
Surgical treatment is typically reserved for men with a severe penile curvature. Surgical procedures may include:
- Tunica Tightening / Plication: This procedure involves tightening of the side of the penis opposite the curve using non-absorbable sutures.
- Grafting: In this procedure, the Peyronie’s plaque is excised and replaced with a graft of porcine tissue or synthetic material.
- Penile Prosthesis Implant